The ?-chain in a ghanaian adult, homozygous for hereditary persistence of fetal haemoglobin

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dc.contributor.authorKamuzora, H.
dc.contributor.authorRingelhann, B.
dc.contributor.authorKonotey-Ahulu, F.I.
dc.contributor.authorLehmann, H.
dc.contributor.authorLorkin, P.A.
dc.date.accessioned2025-11-19T17:25:25Z
dc.date.issued1974
dc.description.abstractFetal haemoglobin consists of ?- and ?-chains. There are two types of human ?-chains: One,(G?) in which residue 136 is one of glycine, and another (A?), in which that position is occupied by a residue of alanine. Some time ago a homozygote for the high persistent fetal haemoglobin gene was found in Ghana whose sole red cell pigment was fetal haemoglobin. The nature of the fetal haemoglobin in this individual has now been determined. It is entirely of the G?-type. � 1974 by S. Karger AG, Basel. � 2015 Elsevier B.V., All rights reserved.
dc.identifier.issn14219662
dc.identifier.issn00015792
dc.identifier.other10.1159/000208291
dc.identifier.urihttps://achimotaschoolarchives.org/handle/123456789/390
dc.language.isoen
dc.sourceActa Haematologica
dc.subjectFetal haemoglobin
dc.subjectHaemoglobinopathies
dc.subjectHereditary persistence of Hb F
dc.subject?-Chains of Hb F
dc.subjecthemoglobin f
dc.subjecthemoglobin gamma chain
dc.subjectbiochemistry
dc.subjecthomozygosity
dc.subjectmajor clinical study
dc.subjecttheoretical study
dc.subjectAmino Acids
dc.subjectCellulose
dc.subjectChromatography
dc.subjectElectrophoresis, Paper
dc.subjectFetal Hemoglobin
dc.subjectGhana
dc.subjectHemoglobinopathies
dc.subjectHomozygote
dc.subjectHumans
dc.subjectImmunoglobulin Fragments
dc.subjectImmunoglobulin Heavy Chains
dc.subjectPeptides
dc.subjectTrypsin
dc.titleThe ?-chain in a ghanaian adult, homozygous for hereditary persistence of fetal haemoglobin
dc.typeArticle

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