The Sickle Cell Diseases: Clinical Manifestations Including the Sickle Crisis
Abstract
Working definitions of "sickle cell disease, sickle-cell trait, and the sickle crisis are given. The pathogenesis of the crisis is explained and the complications of the disease are presented in a quantitative manner. The need to look at the patient as a whole and to assess the natural history of the disease against the background of an often prevalent social and environmental pathologic condition is stressed. A call for effective public health measures, including raising of living standards and providing comprehensive health care facilities for sickle cell disease patients is made. � 1974, American Medical Association. All rights reserved. � 2015 Elsevier B.V., All rights reserved.
Description
Keywords
classification, etiology, pediatrics, prevention, review, sickle cell anemia, sickle cell crisis, Adult, Anemia, Hemolytic, Anemia, Sickle Cell, Child, Child, Preschool, Comprehensive Health Care, Female, Foot Diseases, Genotype, Ghana, Glucosephosphate Dehydrogenase Deficiency, Growth Disorders, Hand, Hematuria, Human, Infant, Male, Negroid Race, Pain, Pallor, Phenotype, Public Health, Socioeconomic Factors, Terminology