Torrential Epistaxis with Symmetrical Facial-skin Ulceration in Sickle-cell Anaemia

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Symmetrical facial-skin ulceration associated with severe epistaxis is described for the first time in sickle-cell anaemia. It is suggested that extreme reflex vasoconstriction in the skin of the face precipitated skin necrosis. The variability of the presenting symptoms in sickle-cell disease is underlined. � 1965, British Medical Journal Publishing Group. All rights reserved. � 2016 Elsevier B.V., All rights reserved.

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adolescent, Africa, African American, article, case report, epistaxis, female, human, Negro, sickle cell anemia, skin disease, skin ulcer, Adolescent, Africa, Western, African Americans, African Continental Ancestry Group, Anemia, Sickle Cell, Epistaxis, Facial Dermatoses, Female, Humans, Skin Ulcer

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